Great interview. It seems that are biggest problems are pre-op and post-op: getting patients evaluated and on the wait list in a timely manner, and honoring their place on the list, and then having structured surveillance of the new graft to protect it and extend longevity. In a world where donated organs are a limited resource, I think solving those issues is imperative. Blending in MA patients in IOTA is also important; that 50% penetration will only get larger during the six years of this demonstration.
Mark, thank you. Well said, I agree these seem to be biggest opportunities and unmet needs. I wasn't as familiar with how MA mix will work, so I'm hoping to explore that a bit further as things progress with IOTA.
![Signals From [Space]](https://substackcdn.com/image/fetch/w_80,h_80,c_fill,f_webp,q_auto:good,fl_progressive:steep,g_auto/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F55686857-6b99-45a6-ac0f-09c9f023f2a0_500x500.png)
![Signals From [Space]](https://substackcdn.com/image/fetch/w_36,h_36,c_fill,f_webp,q_auto:good,fl_progressive:steep,g_auto/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F55686857-6b99-45a6-ac0f-09c9f023f2a0_500x500.png)
![Signals From [Space]](https://substackcdn.com/image/fetch/e_trim:10:white/e_trim:10:transparent/h_72,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F4d588ac1-7fac-4bd4-829d-fc7b4e8f1326_1512x288.png)
Great interview. It seems that are biggest problems are pre-op and post-op: getting patients evaluated and on the wait list in a timely manner, and honoring their place on the list, and then having structured surveillance of the new graft to protect it and extend longevity. In a world where donated organs are a limited resource, I think solving those issues is imperative. Blending in MA patients in IOTA is also important; that 50% penetration will only get larger during the six years of this demonstration.
Mark, thank you. Well said, I agree these seem to be biggest opportunities and unmet needs. I wasn't as familiar with how MA mix will work, so I'm hoping to explore that a bit further as things progress with IOTA.